As of general principle, your Clonazepam dosage may vary on:
- The medical condition being treated
- Your age
- Other medications you may be taking
- Other medical conditions you may have.

Some considerations for people taking clonazepam include the following:

- Clonazepam comes in tablets and wafers (orally disintegrating tablets). Clonazepam is taken by mouth, usually two or three times daily.
- Clonazepam wafers will rapidly dissolve in your mouth, without any need for water. These wafers are especially useful for children who have difficulty swallowing tablets.
- Clonazepam can be taken with or without food. If clonazepam bothers your stomach, try taking it with food.

Generally, the recommended starting clonazepam dosage for treating adults with seizures is 0.5 mg three times a day. For treating panic disorder, the starting clonazepam dosing is typically 0.25 mg twice daily. Your age, other medical conditions you have, and other medications you are taking can affect the clonazepam dose your healthcare provider prescribes.

Some specialists recommend that, for seizures in adults the initial dose to be 1.5 mg daily in 3 divided doses. Dosage may be increased by 0.5 to 1 mg daily every 3 days until seizures are controlled or side effects preclude further increases in dose. The maximum dose is 20 mg daily. The initial dose for panic disorders is 0.25 mg twice daily. The dose may be increased to the target dose of 1 mg daily after 3 days.

Here is an example of common Clonazepam dosages by indication:

Absence Epilepsy:
1 tablet (0.5 mg) by oral route 3 times per day
2 tablets (1 mg) by oral route 3 times per day
1 tablet (1 mg) by oral route 3 times per day
2 tablets (2 mg) by oral route 3 times per day
1 tablet (2 mg) by oral route 3 times per day
2 tablets (4 mg) by oral route 3 times per day

Atonic Seizures:
1 tablet (0.5 mg) by oral route 3 times per day
2 tablets (1 mg) by oral route 3 times per day
1 tablet (1 mg) by oral route 3 times per day
2 tablets (2 mg) by oral route 3 times per day
1 tablet (2 mg) by oral route 3 times per day
2 tablets (4 mg) by oral route 3 times per day

Lennox-Gastaut Epilepsy    :
1 tablet (0.5 mg) by oral route 3 times per day
2 tablets (1 mg) by oral route 3 times per day
1 tablet (1 mg) by oral route 3 times per day
2 tablets (2 mg) by oral route 3 times per day
1 tablet (2 mg) by oral route 3 times per day
2 tablets (4 mg) by oral route 3 times per day

Myoclonic Epilepsy:
1 tablet (0.5 mg) by oral route 3 times per day
2 tablets (1 mg) by oral route 3 times per day
1 tablet (1 mg) by oral route 3 times per day
2 tablets (2 mg) by oral route 3 times per day
1 tablet (2 mg) by oral route 3 times per day
2 tablets (4 mg) by oral route 3 times per day

Panic Disorder:
1 tablet (0.5 mg) by oral route 2 times per day
2 tablets (1 mg) by oral route 2 times per day
1 tablet (1 mg) by oral route 2 times per day
2 tablets (2 mg) by oral route 2 times per day
1 tablet (2 mg) by oral route 2 times per day

Do not exceed the recommended dosage or take this medicine for longer than prescribed. Exceeding the recommended dose or taking this medicine for longer than prescribed may be habit forming.

* Follow the directions for using this medicine provided by your doctor.
* Store this medicine at room temperature, away from heat and light.
* Take this medicine everyday at evenly spaced intervals.
* If you miss a dose of this medicine and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
* This medicine may be taken with food if it upsets your stomach.

Clonazepam overdose

Clonazepam overdose symptoms may vary. Like those produced by other CNS depressants, they include somnolence, confusion, drowsiness, coma and diminished reflexes.

Life-threatening overdose symptoms are more likely if clonazepam is combined with alcohol or other medications.

If you or someone you know may have used more than the recommended dose of this medicine, contact your local poison control center or emergency room immediately.

The treatment for a clonazepam overdose will vary.

Treatment includes monitoring of respiration, pulse and blood pressure, general supportive measures and immediate gastric lavage. Intravenous fluids should be administered and an adequate airway maintained. Hypotension may be combated by the use of levarterenol or metaraminol. Methylphenidate or caffeine and sodium benzoate may be given to combat CNS depression. Dialysis is of no known value.
If the clonazepam overdose was recent, the healthcare provider may use certain medicines or place a tube into the stomach to “pump the stomach.” Flumazenil (Romazicon®), an antidote for a benzodiazepine overdose, may also be helpful (although this treatment can be dangerous in people taking clonazepam for seizures). Treatment also involves supportive care, which consists of treating the symptoms that occur as a result of the overdose. For example, supportive treatment options may include:
* Fluids through an intravenous line (IV)
* Careful monitoring of blood pressure, heart rate, and breathing
* Other treatments based on the complications that occur.

We put emphasis on the fact that it is important that you seek medical attention immediately if you believe that you may have overdosed on clonazepam.

Chronic exposure to Valium causes physical adaptations in the brain to counteract the drug’s effects. This is known as a tolerance and physical dependence. When the drug is removed or dosage reduced in an individual physically dependent on Valium, numerous withdrawal symptoms both physical and psychological may appear and will remain present until the body reverses the physical dependence by making adaptions to the drug-free environment and thus returning the brain to normal function. Generally the higher the dose and the longer a Valium is used and the more rapidly a Valium is discontinued then the more likely severe withdrawal symptoms will occur. However, severe withdrawal symptoms can still occur during gradual dose reduction or from relatively low doses.

In certain selected patient groups the occurrence of withdrawal symptoms is as high as 100%, whereas in unselected patient groups more than 50% of subjects are able to discontinue Valium with mild or even no withdrawal symptoms at all. Withdrawal symptoms may persist for weeks or months after cessation of Valium. In a smaller subset of patients withdrawal symptoms may continue at a sub acute level for many months or even a year or more. Long term use of Valium may lead to withdrawal like symptoms emerging despite a constant therapeutic dose. Correctly attributing previously misdiagnosed withdrawal symptoms such as anxiety to the withdrawal effects of Valium, individualised taper strategies according to withdrawal severity, the addition of alternative strategies such as reassurance and referral to Valium withdrawal support groups increase the success rate of withdrawal.Withdrawal symptoms can resemble psychiatric symptoms which doctors often interpret as evidence for the need of Valium which in turn leads to withdrawal failure and reinstatement of Valium, often to higher doses.

If an individual is using drugs and he or she decides to stop using, they can… right? Not really. Why, you ask. Quite simple. It can be summed up all in one word: withdrawal. Drug use is more than just a bad habit. Drug use is addictive not only because psychologically an individual feels compelled to use, but also because his or her body develops a physical dependence. When this dependence develops and drug use is abruptly discontinued, symptoms of withdrawal can and usually do arise. Basically, the body goes into shock. The exact symptoms of withdrawal will change depending on the drug the individual is dependent upon. Here we will discuss some of the different withdrawal states that can occur.

Valium depresses the nervous system much like alcohol and is abused by all segments of society. Valium is both physically and psychologically addicting and as is considered one of the toughest addictions to break. With chronic use, its abuse potential is high. Withdrawal symptoms can be seen after only 2 or 3 days of repeated use.

Tolerance to Valium builds quickly and is the effect of cellular adaptive changes or enhanced drug metabolism. This tolerance develops over days, weeks, or months is a diminished response associated with chronic use of this drug.

All benzodiazepines, even when used as recommended, may produce emotional and/or physical dependence. Valium has the potential to cause severe emotional and physical dependence in some patients and these individuals may find it exceedingly difficult to stop using. It is important that your physician help you discontinue this medication in a careful and safe manner to avoid severe withdrawal.

To abruptly stop Valium after an extended period of use is extremely dangerous and can cause seizures and sometimes death. Discontinuation of the medication must include a physician supervised gradual taper schedule and/or adjunct medications to minimize acute withdrawal.

Essentially, withdrawal symptoms from Valium are like the mirror of its therapeutic effects. Valium withdrawal can produce especially severe withdrawal symptoms similar to those in alcohol and barbiturate withdrawal, including jittery, shaky feelings and any of the following: rapid heartbeat, tremor, insomnia, sweating, irritability, anxiety, blurred vision, decreased concentration, decreased mental clarity, diarrhea, heightened awareness of noise or bright lights, impaired sense of smell, loss of appetite, loss of weight, muscle cramps, seizures, tingling sensation, and agitation. In more extreme cases, typically associated with sudden cessation of the drug, users may experience convulsions, tremor, abdominal and muscle cramps, vomiting and sweating. After extended abuse, abrupt discontinuation should be avoided and a gradual dosage tapering schedule carefully followed.

Obviously, the severity of withdrawal symptoms is directly related to the amount of the drug taken and the length of time over which it has been taken.

Some of the withdrawal symptoms are identical to the symptoms for which the medication was originally prescribed. The ability to determine the difference between relapse and rebound is very important during the withdrawal phase and can often lead to a misdiagnosis. Withdrawal symptoms from low dose dependence typically last 6–12 months and gradually improve over that time period. Symptoms may lack a psychological cause and can fluctuate in intensity with periods of good and bad days until eventual recovery. For this reason, many experts agree that after withdrawal from long term or even fairly short term use of benzodiazepine drugs, at least six months should have elapsed prior to re-evaluating the symptoms and updating a diagnosis.

The following symptoms may emerge during gradual dosage reduction but can usually be reduced in intensity or eliminated altogether by reducing the rate of reduction:

* Anxiety, possible terror and panic attacks
* Agitation and restlessness
* Hypochondriasis
* Dilated pupils
* Impaired concentration
* Nightmares
* Insomnia
* Muscular spasms, cramps or fasciculations
* Electric shock sensations
* Blurred vision
* Dizziness
* Dry mouth
* Aches and pains
* Hearing impairment
* Taste and smell disturbances
* Chest pain
* Flu like symptoms
* Impaired memory and concentration[37]
* Increased sensitivity to sound
* Increased urinary frequency
* Numbness and tingling
* Hot and cold flushes
* Headache
* Rebound REM sleep
* Stiffness
* Fatigue and weakness
* Hyperosmia
* Restless legs syndrome
* Metallic taste
* Photophobia
* Paranoia
* Hypnagogia-hallucinations
* Nausea and vomiting
* Elevation in blood pressure
* Tachycardia
* Hypertension
* Postural hypotension
* Depression (can be severe), possible suicidal ideation
* Tremor
* Perspiration
* Loss of appetite and weight loss
* Dysphoria
* Depersonalization
* Derealisation (Feelings of unreality)
* Obsessive compulsive disorder
* Tinnitus
* Paraesthesia
* Visual disturbances
* Mood swings
* Indecision
* Gastrointestinal problems (Irritable bowel syndrome)

An abrupt or over-rapid discontinuation of benzodiazepines may result in a more serious and very unpleasant withdrawal syndrome that may additionally result in:

* Convulsions, which may result in death
* Catatonia, which may result in death
* Coma (rare)
* Suicide
* Attempted suicide
* Suicidal ideation
* Self harm
* Hyperthermia
* Delusions
* Homicidal ideation
* Urges to shout, throw, break things or to harm someone
* Violence
* Post Traumatic Stress Disorder
* Organic brain syndrome
* Psychosis
* Confusion
* Mania
* Neuroleptic malignant syndrome like event (rare)
* Delirium tremens

Some people experience little or no withdrawal when stopping long term benzodiazepine usage. It is not known for sure why there is such a variation between patients but recent research in animals suggests that withdrawal from sedative hypnotic drugs may be influenced by a genetic component. As withdrawal progresses patients often find that their physical and mental health improves with improved mood and improved cognition.

Ordering Valium online with no prescription became lately extremely difficult. However, our website can still lead you to safe and secure pharmacies that are selling Valium without a medical prescription required. So feel free to click on the button above and place your order online, hassle-free. We have to remind you that by all means we encourage you to consult a physician before taking Valium.

Valium – characteristics, usage, side effects

Valium is a member of the benzodiazepine drug family. Benzodiazepines are sedatives that cause dose-related depression of the central nervous system.

The chemical name of Valium  is 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one. It is a colorless to light yellow crystalline compound, insoluble in water. The empiricalformula is C ₁₆H₁₃ClN₂O and the molecular weight is 284.75. The structural formula is as follows:

Valium is available for oral administration as tablets containing 2 mg, 5 mg or 10 mg diazepam. In addition to the active ingredient diazepam, each tablet contains the following inactive ingredients: anhydrous lactose, corn starch, pregelatinized starch and calcium stearate with the following dyes: 5-mg tablets contain FD&C Yellow No. 6 and D&C Yellow No. 10; 10-mg tablets contain FD&C Blue No. 1. Valium 2-mg tablets contain no dye.

Benzodiazepines are useful in treating anxiety,  insomnia, seizures, and muscle spasms. It may also be used to treat agitation, shakiness, and hallucinations during alcohol withdrawal and to relieve certain types of muscle pain.

Valium is used for the short-term relief of symptoms related to anxiety disorders. Valium is also used for the treatment of agitation, tremors, delirium, seizures, and hallucinations as a result of alcohol withdrawal. Valium serves for relief of muscle spasms in certain neurological diseases. Valium is used to abort active seizures and can be combined with other drugs in treating severe recurrent seizures.

Valium is very useful in the treatment of status epilepticus and recalcitrant recurrent convulsive seizures.

Valium is a useful premedication for relief of anxiety and apprehension in patients who are to undergo surgical procedures. Intravenous administration takes effect within a few seconds to relieve the anxiety.

Valium no prescription administration:

Take Valium  exactly as directed by your doctor. Take each oral dose with a full glass of water. To ensure the correct dose, measure the liquid forms of Valium  with a dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one. Do not take diazepam more often or in larger doses than is prescribed. Valium  is habit forming. You can become physically and psychologically dependent on the medication. Withdrawal effects may occur if diazepam is stopped suddenly after several weeks of continuous use. Your doctor may recommend a gradual reduction in your dose of [DDET Valium]Valium no prescription Interactions

If Valium is to be administered concomitantly with other drugs, attention should be paid to the possible pharmacological interactions. Particular care should be taken with drugs that enhance the effects of Valium, such as barbiturates, phenothiazines, narcotics and antidepressants.

Valium does not increase or decrease hepatic enzyme activity, and does not alter the metabolism of other compounds. There is no evidence that would suggest Valium alters its own metabolism with chronic administration.

Agents that have an effect on hepatic cytochrome P450 pathways or conjugation can alter the rate of Valium metabolism. These interactions would be expected to be most significant with long-term Valium therapy, and their clinical significance is variable.

* Valium increases the central depressive effects of alcohol, other hypnotics/sedatives (e.g., barbiturates), narcotics, and other muscle relaxants. The euphoriant effects of opioids may be increased, leading to increased risk of psychological dependence.

* Cimetidine, omeprazole, ketoconazole, itraconazole, disulfiram, fluvoxamine, isoniazid, erythromycin, probenecid, propranolol, imipramine, ciprofloxacin, fluoxetine and valproic acid prolong the action of Valium by inhibiting its elimination.

* Alcohol (ethanol) in combination with Valium may cause a synergistic enhancement of the hypotensive properties of benzodiazepines and alcohol.

* Oral contraceptives (“the pill”) significantly decrease the elimination of desmethylValium, a major metabolite of Valium.

* Rifampin, phenytoin, carbamazepine and phenobarbital increase the metabolism of Valium, thus decreasing drug levels and effects.

* Valium increases the serum levels of phenobarbital.

* Nefazodone can cause increased blood levels of benzodiazepines.

* Cisapride may enhance the absorption, and therefore the sedative activity, of Valium.

* Small doses of theophylline may inhibit the action of Valium.

* Valium may block the action of levodopa (used in the treatment of Parkinson’s Disease).

* Valium may alter digoxin serum concentrations.

* Other drugs that may have interactions with Valium include: Antipsychotics (e.g. chlorpromazine), MAO inhibitors, ranitidine.[46]

* Caffeine may antagonise the effects of Valium and vice versa.

* Smoking tobacco can enhance the elimination of Valium and decrease its action.

* Because it acts on the GABA receptor the herb Valerian may produce an adverse effect.

* Foods that acidify the urine can lead to faster absorption and elimination of Valium, reducing drug levels and activity.

* Foods that alkalinize the urine can lead to slower absorption and elimination of Valium, increasing drug levels and activity.

* There are conflicting reports as to whether food in general has any effects on the absorption and activity of orally administered Valium.

Normal dosage of Valium when buying Valium no prescription:

CAUTION:

If under 18 years of age: Safety and effectiveness are not established.

Valium should not be given to children under 6 months of age.

Valium Dosage:

• Children over months of age, 1mg to 2.5mg 3 to 4 times daily.
• 18 to 60 years of age, 2mg to 10mg 2 to 4 times daily.
• Over 60 years of age, 2mg to 2.5mg 1 to 2 times daily (increase as needed).
• Dosages: Actual dosage must be determined by a physician.

Valium Dosage Depending on Disorder:

• Anxiety disorders and the short-term relief of the symptoms of anxiety, 18 to 60 years of age,2mg to 10mg 2 to 4 times daily or time-r el 15-30mg.
• Acute alcohol withdrawal, 18 to 60 years of age, 10mg 3 to 4 times during the first 24 hours the 5mg 3 or 4 times daily.
• Relief of muscle spasm, 18 to 60 years of age, 2mg to 10mg 3 to 4 times daily.
• Convulsive disorders, 18 to 60 years of age, 2mg to 10mg 2 to 4 times daily.
• Status epilepticus:
  • 18 to 60 years of age, IV 5-10mg at 2-5mg/min, up to a maximum dose of 30mg. May repeat in 2-4 hours.
  • Children over 5 years of age, IV 1mg/min q3-5min, up to a maximum dose of 10mg. May repeat in 2-4 hours.
  • Children 1 month to 5 years of age, 0.2-0.5mg/min slowly q2-5min, up to a maximum dose of 5mg.

Missed Dose(s) of Valium : If within one hour take. If over an hour skip and then continue on your normal schedule.

CAUTION! Never Take a Double Dose of Valium!

Valium no prescription – Overdose

An individual that has consumed too much Valium will typically display one or more of the following symptoms in the period up around four hours immediately following a suspected overdose.:

* Drowsiness

* Mental confusion

* Hypotension

* Impaired motor functions

o Impaired reflexes

o Impaired coordination

o Impaired balance

o Dizziness

* Coma

Although not usually fatal when taken alone, a Valium overdose is considered a medical emergency and generally requires the immediate attention of medical personnel. The antidote for an overdose of Valium (or any other benzodiazepine) is flumazenil (Anexate). This drug is only used in cases with severe respiratory depression or cardiovascular complications. Because flumazenil is a short-acting drug, and the effects of Valium can last for days, several doses of flumazenil may be necessary. Artificial respiration and stabilization of cardiovascular functions may also be necessary. Although not routinely indicated, activated charcoal can be used for decontamination of the stomach following a Valium overdose. Emesis is contraindicated. Dialysis is minimally effective. Hypotension may be treated with levarterenol or metaraminol.

The oral LD50 (lethal dose in 50% of the population) of Valium is 720 mg/kg in mice and 1240 mg/kg in rats. D. J. Greenblatt and colleagues reported in 1978 on two patients who had taken 500 and 2000 mg of Valium, respectively, went into moderately-deep comas, and were discharged within 48 hours without having experienced important complications, in spite of having high concentrations of Valium and its metabolites—desmethylValium, oxazepam, and temazepam—according to samples taken in the hospital and as follow-up.

Overdoses of Valium with alcohol, opiates and/or other depressants may be fatal.

Valium no prescription – Contraindications

Use of Valium should be avoided, when possible, in individuals with the following conditions:

* Ataxia

* Severe hypoventilation

* Acute narrow-angle glaucoma

* Severe hepatic deficiencies (hepatitis and liver cirrhosis decrease elimination by a factor of 2)

* Severe renal deficiencies (e.g. patients on dialysis)

* Liver disorders

* Severe respiratory disorders

* Severe sleep apnea

* Severe depression, particularly when accompanied by suicidal tendencies

* Psychosis

* Pregnancy or breast feeding

* Caution required in elderly or debilitated patients

* Coma or shock

* Abrupt discontinuation of therapy

* Acute intoxication with alcohol, narcotics, or other psychoactive substances (with the exception of some hallucinogens, where it is occasionally used as a treatment for overdose)

* History of alcohol or drug dependence

* Myasthenia gravis, or MG, an autoimmune disorder causing marked fatiguability.

* Hypersensitivity or allergy to any drug in the benzodiazepine class

Valium no prescription Special caution needed

* Benzodiazepines require special precaution if used in the alcohol- or drug-dependent individuals and individuals with comorbid psychiatric disorders.

* Pediatric patients

o Less than 18 years of age – Treatment usually not indicated, except treatment of epilepsy, and pre-/postoperative treatment. The smallest possible effective dose should be used for this group of patients.

o Under 6 months of age – Safety and effectiveness have not been established; Valium should not be given to individuals in this age group.

* Elderly and very ill patients – Possibility that apnea and/or cardiac arrest may occur. Concomitant use of other central nervous system depressants increases this risk. The smallest possible effective dose should be used for this group of patients.

Valium may also be dangerous in geriatric patients owing to a significant increased risk of falls.

* I.V. or I.M. injections in hypotensive individuals or those in shock should be administered carefully and vital signs should be monitored.

* Benzodiazepines such as Valium are lipophilic and rapidly penetrate membranes, and, therefore, rapidly cross over into the placenta with significant uptake of the drug. Use of benzodiazepines including Valium in late pregnancy, especially high doses, may result in floppy infant syndrome.

Valium no prescription Pregnancy

Valium when taken late in pregnancy, during the third trimester, causes a definite risk of a severe benzodiazepine withdrawal syndrome in the neonate with symptoms including hypotonia, and reluctance to suck, to apnoeic spells, cyanosis, and impaired metabolic responses to cold stress. Floppy infant syndrome and sedation in the newborn may also occur. Symptoms of floppy infant syndrome and the neonatal benzodiazepine withdrawal syndrome have been reported to persist from hours to months after birth.

Valium no prescription – Tolerance and physical dependence

Valium as with other benzodiazepine drugs can cause tolerance, physical dependence, addiction and what is known as the benzodiazepine withdrawal syndrome. Withdrawal from Valium or other benzodiazepines often leads to withdrawal symptoms that are similar to those seen during barbiturate or alcohol withdrawal. The higher the dose and the longer the drug is taken for the greater the risk of experiencing unpleasant withdrawal symptoms. Withdrawal symptoms can occur from standard dosages and also after short-term use. Benzodiazepine treatment should be discontinued as soon as possible via a slow and gradual dose reduction regime.It has been shown in a clinical study that between 50–100% of patients on low-dose long-term Valium therapy are physically dependent on their medication, and experience withdrawal symptoms upon discontinuation from a dose taper.The difference in rates of withdrawal (50–100%) varies depending on the patient sample being investigated. For example a random sample of long term benzodiazepine users typically finds that around 50% will experience little or no withdrawal symptoms and the other 50% experiencing notable withdrawal symptoms. Certain select patient groups will show a higher rate of notable withdrawal symptoms, up to 100%. Rebound anxiety, more severe than baseline anxiety, is also a common withdrawal symptom when discontinuing Valium or other benzodiazepines. Valium is therefore only recommended for short-term therapy at the lowest possible dose owing to risks of severe withdrawal problems from low doses even after gradual reduction. There is a significant risk of pharmacological dependence on Valium and patients experiencing symptoms of benzodiazepine withdrawal syndrome if it is taken for 6 weeks or longer. In humans tolerance to the anticonvulsant effects of Valium occurs frequently.